Sustaining remission in juvenile dermatomyositis
نویسندگان
چکیده
منابع مشابه
The PRINTO provisional definition of remission in juvenile dermatomyositis
Methods 275 patients in active phase of JDM <18 years, median disease duration 7.7 months, were evaluated at baseline and 24 months. Out of 275 patients, all patients (39/ 275) who were off treatment at 24 months were defined as being in clinical remission and were included as the “gold standard” group. A random sample of patients (n=78) who were in an active phase of JDM at baseline and on med...
متن کاملRecurrence of juvenile dermatomyositis 8 years after remission
CDASI: Cutaneous Dermatomyositis Area and Severity Index JDM: juvenile dermatomyositis MTX: methotrexate mPSL: methylprednisolone PSL: prednisolone INTRODUCTION Juvenile dermatomyositis (JDM) is a chronic inflammatory disease characterized by typical skin lesions and muscle weakness, which occurs in children and adolescents younger than 16 years. JDM is classified into 3 clinical types accordin...
متن کاملJuvenile dermatomyositis.
Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other a...
متن کاملJuvenile dermatomyositis.
The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them. The electromyogram (EMG) was performed in 6 and was found abnormal in five. All the...
متن کاملJuvenile Dermatomyositis in Pregnancy
Juvenile dermatomyositis has variable clinical presentations both in and outside of pregnancy. A literature review indicated that optimal maternal and fetal outcomes can be anticipated when the pregnancy is undertaken while the disease is in remission. Poorer outcomes are associated with flare-up of the disease in early pregnancy compared with exacerbation in the second or third trimester, when...
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ژورنال
عنوان ژورنال: Nature Reviews Rheumatology
سال: 2009
ISSN: 1759-4790,1759-4804
DOI: 10.1038/nrrheum.2009.123